Materials and Methodsより Pregnant albino Sprague-Dawley rats were obtained from the Simonsen Laboratories, Inc., Gilroy, California, 5 days before parturition. On the 1st day after birth the litter size was reduced to eight and on the 9th day the young were injected subcutaneously between the scapulae. In one experiment paired animals from each of three litters were administered 20μl (12.5μCi) of either sodium DL-β-hydoxy[3-14C]butyrate, sodium [3-14C]acetoacetate, sodium [2-14C]acetate, or potassium RS-[2-14C]mevalonate. Littermates were scarificed at 4, 24, and 72 hours after injection.
